I personally think it’s an obvious thing that peope build against.

Aka

emp hardend

It’s a common thing. EMP discharge devices and anti-material weapons are common uses against cybernetics. The problem is dependant on cost.

Most cyberware consists of limb replacements. These use a mix of hydraulics and myomer (artificial muscle) with simple electrical systems and an interface chip to control them. EMP will disrupt the interface on cheaper stuff, but the more expensive cybernetics uses optronics and repurposes natural nerve systems, making it resistant.

Anti-material weapons and ‘cracking’ weapons are pointless against normal flesh creatures, as it just punches a hole clean through them, but can wreck cybernetic limbs.

Most special police and intelligence services have anti-cyborg departments, and cybernetics has a host of drawbacks — cancer, phantom limb syndrome, emotional problems and toxic shock — that only those with no choice tend to use it, and it’s expensive enough that most people can’t afford it.

Since each race’s nervous systems and immune reactions are different, most times interface chips are produced by the races themselves.

While civilian cybersystems are generic (and many are made by salarian or quarian companies), no military is going to install ANYTHING not produced by their own military production systems from the ground up.

The race with the most anti-cyborg stuff is, amusingly, the quarians. Not only are they FAR more advanced in terms of what they can do with cybernetics and understanding it, their weapons (designed to combat EMP hardened geth) are outstanding at overloading and/or disrupting cybernetic systems.