Main Cast - Protagonists
 | Sara Shepard | Art by : AllNighterProductions |
 | Liara T'soni | Art by : AllNighterProductions |
 | Garrus Vakarian | Art by : Gobeur (deviantart) |
OSABC Cast - Systems Alliance
 | Charles Pressly | Art by : in-game image | |||
 | Diana Friggs | Art by : Joyreactor | |||
 | Tradius Ahern | Art by : AllNighterProductions | |||
 | Stephen Hackett | Art by : Yuhime (deviantart) | |||
 | Ivan Dragunov | Art by : AllNighterProductions | |||
 | Karin Chakwas | Art by : CLC1997 (deviantart) | |||
 | Alfred Jiong | Art by : NikitaStewart | |||
 | Susan D'Alte | Art by : NikitaStewart |
OSABC Cast - Main Antagonists
 | Benezia T'Soni | Art by : AllNighterProductions | |||
 | Saren Arterius | Art by : Sandara (DA) | |||
 | Richard Williams | Art by : Mr. Boston (DA) | |||
 | Tetrimus Rakora | Art by : NikitaFrost | |||
 | Tazzik | Art by : Skeletang (DA) | |||
 | P. | Art by : CLC1997 (deviantart) | |||
 | Ganar Okeer | Art by : Skarita (DA) | |||
 | The Shadow Broker | Art by : Meken |
Supporting Cast
 | The Shifter | Art by : Bioware | |||
 | Matriarch Trellani | Art by : LuckyFK | |||
 | Uressa T'Shora | Art by : Isbjorg (DA) |